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位于热带海域的一座无名小岛，蔚蓝大海与金色沙滩接壤之初，飞机破碎的残骸伴随着遇难乘客的恸哭哀号，揭开了一个神秘故事的序幕。2004年，815航班在前往目的地的途中突遭变故，坠毁在这座小岛，机上仅有杰克·谢帕德（马修·福克斯 Matthew Fox 饰）、凯特·奥斯汀（伊万杰琳·莉莉 Nicole Evangeline Lilly 饰）等48人侥幸逃生。最初的惊恐过后，不同年龄、职业、国别、民族、背景的一群人，在这个与世隔绝的逼仄且食物紧缺的空间内不可避免发生冲突与碰撞，与此同时，小岛上似乎还隐藏着某种未知且极具威胁的生物，而他们的一举一动又仿佛被一双双充满智慧但又神秘莫测的眼睛所监视。 不可预测的未来，接二连三的谜团，以及仿佛永远无法到来的救援队，让幸存者们不知所措……。1947. On a beach in Normandy, Madeleine, a waitress and young mother, meets François, a wealthy, and cultivated student. They hit it off immediately, as though it were fate. But as their destinies intertwine, it’s obvious what Madeline wants to leave behind, while the world that Francois is running from is only slowly revealed.。Dee, a non-binary freelance illustrator, is locked into a lease they can't afford. Dee's younger sister, Amy, enacts a plan to find the perfect roommate. Enter Rachel, a queer British bartender eager to fit in as a Canadian. Months later, things go from cool to not-so-cool when Rachel reveals a startling secret - she's claimed Dee as a common-law partner to evade being deported...。